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BioCentury
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BioCentury | Mar 5, 2024
Discovery & Translation

Distillery spotlight: new Alzheimer’s mechanisms from academia

BioCentury’s survey of the 2023 translational literature highlights a cluster of neuron-targeting mechanisms for Alzheimer’s disease 
BioCentury | Jul 18, 2023
Distillery Therapeutics

Targeting ARHGAP11A for Alzheimer's disease

BioCentury | Aug 27, 2021
Distillery Therapeutics

CRISPR-Cas9 deletion of mutant APP to treat Alzheimer’s

BioCentury | Apr 7, 2021
Distillery Therapeutics

RECK, an inhibitor of amyloid precursor protein cleavage, as a target for Alzheimer’s

DISEASE CATEGORY: Neurology
INDICATION: Alzheimer’s disease Blocking RECK, a membrane-tethered inhibitor of APP-cleaving enzyme ADAM10, could treat Alzheimer’s disease. Levels of
BioCentury | Feb 11, 2020
Product Development

Alzheimer’s prevention replays the same amyloid failures as the treatment setting

Lilly’s solanezumab, Roche’s gantenerumab miss DIAN-TU endpoint in presymptomatic AD patients
BioCentury | Jun 11, 2019
Distillery Therapeutics

PSEN1 inhibition could treat T cell ALL

BioCentury | May 4, 2019
Product Development

How the amyloid hypothesis holds its grip

Why pharmas can’t let go of the amyloid hypothesis of Alzheimer’s disease
BioCentury | Mar 25, 2019
Distillery Therapeutics

Inhibiting EFR3A to treat Alzheimer's disease

BioCentury | Jan 30, 2019
Distillery Therapeutics

Neurology; cardiovascular

BioCentury | Jan 4, 2019
Tools & Techniques

Making AD mice as diverse as patients

How adding genetic diversity to Alzheimer’s mice could help define responders
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