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- Company Profiles
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Explore BCIQ profiles by entering a target name.
BioCentury | Jan 26, 2024
Product Development
Growing IL-18 field looks to enhance cell therapies via decoy evasion
As more companies bring IL-18 into their cancer pipelines, they also bring new modalities and approaches to the cytokine’s inhibitory decoy receptor
BioCentury | Dec 20, 2023
Deals
Dec. 19 Quick Takes: Ionis, Otsuka in European deal for HAE therapy
Plus: Carmot spinout Kimia raises $55M series A round, CureVac tumbles on loss in patent case and more from Lassen, Atavistik, Crinetics, Merck and CSL
BioCentury | Dec 19, 2023
Deals
Compugen gets badly-needed lift as Gilead strikes deal for IL-18 program
Stock gain could be enough to keep Israel-based biotech above delisting threshold
BioCentury | Dec 7, 2022
Product Development
ASH22 could be IL-18’s watershed moment
CAR T data at ASH could trigger more development in one of oncology’s less crowded cytokine spaces
BioCentury | Jan 29, 2022
Product Development
Simcha pressure-testing engineered IL-18 with $40 million series B
Founded by Aaron Ring, Yale spinout is exploring its lead candidate’s potential as a cancer monotherapy while building out its management team
BioCentury | Jun 25, 2020
Emerging Company Profile
Simcha launches with $25M WuXi-led series A, new take on IL-18 for cancer
With IP from a Yale lab, Simcha hopes its IL-18 variant will circumvent a resistance mechanism in tumors
BioCentury | Jun 9, 2016
Translation in Brief
Stopping sepsis
Two new methods could protect against sepsis in adults and neonatal infants
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