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BioCentury
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BioCentury | Aug 23, 2024
Emerging Company Profile

Borealis: Versant, Novartis launch Chinook’s RNA-targeting sequel

The research team behind Chinook are taking on renal diseases with cell type-specific delivery of oligonucleotide therapies.
BioCentury | May 30, 2024
Product Development

Renal therapies get disease-specific

Endpoint innovation and success stories are driving a surge in renal disease drug development
BioCentury | Jan 6, 2024
Finance

Jan. 5 Quick Takes: Metagenomi, ArriVent file for IPO

Plus: Immunic eyes $240M private placement and updates from Applied Therapeutics and Novartis  
BioCentury | Nov 17, 2023
Product Development

AstraZeneca looks to new CKD combinations to extend Farxiga’s reign

AZ is moving Farxiga combinations into Phase III testing that it believes can help reach underserved patient subsets 
BioCentury | Oct 31, 2023
Finance

Oct. 30 Quick Takes: VCs pile in for MapLight’s $225M series C

Plus: Deciphera gets lift from TGCT readout and updates from Hengrui, Merck KGaA, AnHeart, Nippon Kayaku, Novartis, GSK and more
BioCentury | Jun 12, 2023
Deals

Seeking high-value drugs, Novartis adds kidney franchise in $3.2B Chinook takeout

Biotech’s later-stage candidates give pharma two chances at a blockbuster, starting with IgA nephropathy indication amid rising competition
BioCentury | Feb 18, 2023
Regulation

FDA’s Filspari approval opens Travere’s two-year window

Travere aims to establish Filspari as standard of care in IgA nephropathy, even with the drug’s liver toxicity monitoring and restricted label
BioCentury | Aug 31, 2021
Regulation

Turning biomarkers into surrogates, starting with the familiar 

Mining decades of clinical practice, three fields are making surrogate endpoints out of common prognostic markers
BioCentury | Aug 16, 2021
Product Development

Travere readout in IgA nephropathy sets up accelerated path to rival Calliditas’ therapy

Positive interim data for sparsentan, a dual angiotensin and endothelin receptor antagonist
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