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BioCentury
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BioCentury | May 24, 2023
Finance

May 23 Quick Takes: VCs back cancer play Larkspur with $35.5M

Plus: PTC reports vatiquinone Phase III miss, discontinuation of gene therapies and updates from Innoviva, Pfizer, Wave, Arrowhead, Icosavax and more
BioCentury | Mar 2, 2023
Data Byte

At least nine PDUFA dates on deck in March

Decisions include leniolisib and trofinetide, both of which could be the first drugs approved for their indications 
BioCentury | Aug 23, 2022
Product Development

The new modality pipeline against ANGPTL3 grows with Verve’s new program

At least two gene editing therapies and three RNA therapies against ANGPTL3 set to compete in dyslipidemia indications
BioCentury | Jan 31, 2022
Deals

After review of Phase IIb data, Pfizer hands back CV program to Ionis

The pharma sunk $325M into vupanorsen, but won’t get its ‘mega-blockbuster’ in cardiovascular indications
BioCentury | Dec 23, 2021
Product Development

First-in-class drugs fill FDA’s 2021 class of new approvals

Products against new targets accounted for nearly one third of NMEs, and fewer of them were for cancer than you might think
BioCentury | Nov 25, 2021
Product Development

Nov. 24 Quick Takes: Pfizer’s vupanorsen meets in Phase IIb

Plus Selecta’s clinical hold, Allorion’s fund-raising and a Philogen-Janssen deal
BioCentury | Mar 5, 2021
Translation in Brief

A stem cell therapy for brain metastases in breast cancer; plus a nanoparticle gene editing delivery tech and more

BioCentury’s roundup of translational news
BioCentury | Feb 12, 2021
Regulation

FDA approval of Regeneron’s Evkeeza brings new drug class to HoFH patients

Regeneron’s Evkeeza evinacumab-dgnb gained FDA approval Thursday as the first ANGPTL3 inhibitor to treat homozygous familial hypercholesterolemia, offering a new mechanism
BioCentury | Aug 31, 2020
Deals

Three years after spinout, Ionis brings back Akcea in $500M acquisition

Three years after Ionis spun out its Akcea unit in an IPO, and nearly a year after the parent company installed a new CEO at the subsidiary, Ionis has chosen to retake full ownership of Akcea in a
BioCentury | Aug 13, 2020
Regulation

Aug. 12 Quick Takes: Approvals for DMD, acute pain; plus Priority Review for Fabry, hypercholesterolemia therapies and more  

FDA approves a second targeted DMD therapyNS Pharma Inc.’s Viltepso viltolarsen received accelerated approval from FDA to treat Duchenne muscular dystrophy in patients amenable to exon 53
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